Each capsule contains: Each capsule contains: Pancreatin 1:8 (180 mg)   Protease 36,000 USP Amylase 36,000 USP Lipase 7200 USP Trypsin 1:75 (35 mg) 2625 USP Chymotrypsin 1:25 (1mg) 25 USP Papain  8,000 FCC Bromelain 600 GDU Lipase (phpergillus oryzae) 20 mg Amylase (phpergillus oryzae) 20 mg   Recommended Dosage Recommended Dosage: 1-2 capsules at the beginning of each meal. Digeston is a very potent enzyme formula that is based uponformulas for which extensive clinical research has been carried out in Europe(primarily Germany, Austria and Switzerland). Its major enzymes are proteases(in the form of pancreatin, bromelain, papain, trypsinand chymotrypsin). These are all proteases or protease-containingdigestive juices, which break down proteins into smaller units – polypeptidesand ultimately into the constituent molecules ; amino-acids. No other formulas have beenas widely researched or tested clinically as have the German preparations:Wobenzym®, Mulstal® and Wobe-Mugos®. Pancreatin is derived from pancreatic digestive juice and ishighly concentrated form. It contains activity of the following enzymes:protease (protein digestion), lipase (lipid digestion), and amylase(carbohydrate digestion). Bromelain is a protease derived from pineapples. Papain is derived from papaya. It is a powerful protease withparticular activity in cleaving peptide bonds involving basic amino-acids,leucine, or glycine. Trypsin has particular activity in cleaving peptides at thecarboxyl group of arginine and lysine. The chymotrypsin usedin Digeston is highly concentrated. It cleaves peptide bonds adjacent toaromatic amino-acids. TREATMENT OF CHRONIC DEGENERATIVE DISEASES For treating chronicdegenerative diseases, where immune complexes, or damaged proteins are a factor,it is the protease part of the formula, which is important, since proteases acton breaking down immune complexes, and damaged or diseased tissue. Manyproteins have attached to them carbohydrate moieties, which require enzymes tobreak them down. Hence a carbohydrase (amylase) is also included in thisformula. For treatment protocol see“Enzymes in the Treatment of Chronic Degenerative Diseases and OtherDisorders.” ENZYMES FOR AIDING DIGESTION In treating digestive problems a potent lipase to break down triglycerides also needs to be included, so that all major food types (proteins, carbohydrates and fats) canbe digested. Insufficient enzyme production leads to maldigestion, resulting in impaired nutrient absorption anddigestive problems. Commonly encountered symptoms are flatulence and digestivedisturbances: constipation or steatorrhea depending on the predominant enzymedeficiency. Deficient enzyme production is found in the following conditions:aging, stress, damage to the intestinal wall (See article on Inflammatory Bowel Disease) and glandular insufficiency. A full diagnostic work-up needs to beperformed, since steatorrhea can be a sign of serious disease. TREATMENT OF CHRONIC DEGENERATIVE DISEASES For treating chronic degenerative diseases, where immune complexes, or damaged proteins are a factor, it is the protease part of the formula, which is important, since proteases act on breaking down immune complexes, and damaged or diseased tissue. Many proteins have attached to them carbohydrate moieties, which require enzymes to break them down. Hence a carbohydrase (amylase) is also included in this formula. For treatment protocol see “Enzymes in the Treatment of Chronic Degenerative Diseases and Other Disorders.”  ENZYMES FOR AIDING DIGESTION In treating digestive problems a potent lipase to break down triglycerides also needs to be included, so that all major food types (proteins, carbohydrates and fats) can be digested. Insufficient enzyme production leads to maldigestion, resulting in impaired nutrient absorption and digestive problems. Commonly encountered symptoms are flatulence and digestive disturbances: constipation or steatorrhea depending on the predominant enzyme deficiency. Deficient enzyme production is found in the following conditions: aging, stress, damage to the intestinal wall (See article on Inflammatory Bowel Disease) and glandular insufficiency. A full diagnostic work-up needs to be performed, since steatorrhea can be a sign of serious disease.