Each capsule contains: B-Sitosterol Complex (Not less than 90% of soya sterols, and not less than 50% beta-sitosterol) 100 mg Quercetin 83.3 mg Genistein (85%) 18.3 mg Recommended Dose: Take two to three capsules twice a day, one hour before a meal. Beta-Sitosterol Beta-sitosterol has been used in such conditions as cancer, autoimmune disorders (e.g. rheumatoid arthritis), and atherosclerosis. It has been used to treat breast, prostate and colon cancer. Beta-sitosterol products are sold in Germany and France by prescription. They are expensive and contain only a small amount of beta-sitosterol. Cancer Beta-sitosterol has been shown to be a cancer preventive agent generally.  Recent laboratory studies show dramatic anti-cancer properties of Beta-sitosterol in reducing cancer cell growth with breast cancer, prostate cancer and colon cancer. It also has shown strong anti-tumor properties in many published studies. In addition, there are many anecdotal cases of cancers going into remission after exposure to beta-sitosterol.  Breast Cancer and Menopause Beta-sitosterol is a powerful inhibitor of breast cancer cells. In one controlled study the number of breast cancer cells was reduced by 66% in five days. Beta-sitosterol has been shown to decrease the severity of night sweats and hot flushes in menopausal women[i]. Prostate Hyperplasia and Cancer Beta-sitosterol has been shown to be one of the most effective treatments for benign prostate hyperplasia (BPH) and other prostate gland disorders. For many years saw palmetto and Pygeum africanum, pumpkinseed oil, stinging nettles, and other natural prostate remedies have been used to treat prostate enlargement. Recent evidence points to beta-sitosterol as being the common factor in all these botanical remedies. 900 g of saw palmetto contain only 300 mg of beta-sitosterol. It has the following biological activities: It inhibits 5-reductase, an enzyme which converts testosterone to dyhydrotestosterone (DHT), which is believed to cause prostate enlargement and activate prostate cancer. It reduces the level of hormone binding hormone, which is the carrier for testosterone, further reducing DHT levels. There is some evidence that it can inhibit prostate cancer cells, by replacing the cholesterol of their cell membrane, which appears to change the intracellular signaling system to cause inhibition of cell division There are several controlled studies that show the efficacy of beta-sitosterol in treating BPH. 50% of men have prostate problems by the age of 60. Most men of 65 have BPH. The first signs are nocturia and dysuria. 97% of all men will be affected with prostate problems during their lifetime. Prostate cancer is the second leading cause of death for men after lung cancer. 90% of prostate cancer goes undetected until it is untreatable and has spread to the lymphatic system. By the age of 50, 35% of men have cancer cells in their prostate. Some studies show that beta-sitosterol can lower PSA, a test that is used to detect prostate cancer. Colon Cancer Beta-sitosterol has been shown to be a powerful inhibitor of colon cancer in humans. There is a significant correlation between beta sitosterol intake and incidence of colon cancer. Beta-sitosterol inhibits tumor growth in colon cancer. Stress-related Disorders and Impaired Immunity Beta-sitosterol has also been shown to have a modulatory effect on the immune system. It boosts the function of T-cells and primes the immune system to function more efficiently. Impaired immunity can be stress-related (physical or emotional) and be a factor in an increased susceptibility to infection, and chronic diseases. Beta-sitosterol reduces stress-related damage by decreasing blood cortisol levels. High cortisol blood levels are believed to be a major factor in stress-related disease. Hypercholesterolemia In addition, over 50 human and animal studies since the 1960’s and published in scientific journals, show that beta-sitosterol has a powerful hypocholesterolemic effect in humans. It has a similar chemical structure to cholesterol. Beta-sitosterol interferes with cholesterol absorption, which prevents the rise in serum cholesterol. In one study (American Journal of Clinical Nutrition) there was 42% decrease in cholesterol absorbed when taking beta-sitosterol before eating scrambled eggs. Beta-sitosterol is also believed to reduce serum cholesterol by inhibiting the intestinal re-absorption of circulating cholesterol, which is secreted in the bile. Quercetin Quercetin is an isoflavone found in many fruits and vegetables. Quercetin has recently been shown to block the action of androgen in androgen-responsive prostate cancer cells[i].  Quercetin may be a non-hormonal means of inhibiting androgen activity. Quercetin is used in the treatment of inflammatory conditions, including prostatitis. Quercetin is also used in the treatment of allergies (asthma, hay fever and eczema). Genistein Genistein is an isoflavone found in soy in small amounts. The action of genistein in inhibiting secretion of PSA in androgen-dependent prostate cancer cell lines has been well documented. Recently, genistein has been shown to block cell proliferation irrespective of PSA signaling pathways[ii]. Genistein also induces cell cycle arrest and death of cancer cells. In experiments conducted in mice genistein decreased prostate cancer tumor growth and in tissue culture it increased the production of p21, a gene that regulates cell growth. This caused cancer cells to die (apoptosis).[iii] Summary of Clinical and Research Studies of Beta-Sitosterol Breast Cancer The study showing a 66% reduction in breast cancer cells was conducted at the University of Buffalo and presented at the annual meeting of the Federation of American Societies of Experimental Biology (May, 1999). Prostate Enlargement (BPH and cancer) Awad et al, Sixth International Conference of Anti-Cancer Research (Kallithea, Greece, 26-10-98) Beta-sitosterol appears to play a role in inhibiting the growth of prostate cancer cells. After exposure to beta-sitosterol for 5 days in vitro, there was a significant inhibition of prostate-cancer cell growth. Beta-sitosterol appears to enhance an intracellular signaling system that signals cells not to divide. Furthermore Awad showed (1996) that beta-sitosterol was a powerful inhibitor of colon cancer growth in human cells. Zahradnik et al showed that beta-sitosterol blocked the expansion of prostate adenoma (tumor) and inhibited prostaglandins that are known to support tumor growth. Beta sitosterol seems to work by inhibiting prostate specific prostaglandins PGE2 and PGF2a, which promote inflammation in the prostate. Tasca et al, in a double blind, placebo-controlled, scientific study, successfully treated BPH patients with obstructive symptomatology caused by prostatic adenoma, (cancer). They used a high percentage of beta-sitosterol, which improved flow rate, other urinary symptoms, and also reduced tumor size. In addition, liver function was enhanced and blood parameters were improved. Numerous international scientific journals have published scientific studies that show that beta-sitosterol is the most effective remedy known for prostate problems. Journals like the International Journal of Immunopharmacol, 1996; The Lancet, 1995; European Journal of Drug Metab, 1997; Anticancer Research, 1996; European Patent EP 287,000, Minerva Urologia, 1985; British Journal of Clinical Pharmacology, 1984; Medizinische Klinik, 1982; European Urology, 1992 and 1994, and Fortsher. Med., 1980. Autoimmune Disorders Immune System Modulation, Int. J Immunopharm. 1996 Rheumatoid Arthritis, Newsletter of the Arthritis Trust of America, 1998 Hypercholesterolemia J. Clin. Invest vol. 82, p. 1833-9 (1988); Human liver microsome studies show beta-sitosterol inhibits cholesterol absorption. Metab. Clin. Exper vol. 38, p. 136-40 (1989) People given beta-sitosterol were shown to lower their cholesterol and triglyceride levels American J. Clin Nutr vol. 59, p. 1325-31 (1994) Vegetarians were shown in the following study, to be protected from fat loading diets by their high intake of beta-sitosterol from plants. [i] Barbara Agpar, American Family Physician, Oct 1999   [ii] Nianzeng Xing, American Association for Cancer Research, 92nd annual meeting, New York, March 2001 [iii] JN Davis et al, Int J Oncol, 16, 1091-7, 200